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chronic liver disease and hepatitis may present with elevated levels Renal impairment : Reduced clearance can contribute to accumulation, though this is rarely clinically significant Solid tumours : Certain malignancies, particularly hepatocellular carcinoma and metastatic disease, may elevate B12 levels [3] Evidence suggests that unexplained markedly elevated B12 levels without supplementation may sometimes be associated with underlying disease
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[6] [2] [3] Severe vitamin B 12 deficiency can damage nerve cells
Inflammatory bowel disease Inflammatory bowel diseases (IBD) are a group of chronic immune-mediated disorders with a relapsingremitting course that affect the gastrointestinal tract, including ulcerative colitis (UC) and Crohns disease (CD)
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