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The clinical characteristics of the low- and high-expression of SLC25A39 subgroups were then compared, and the difference of Gender (P=0.029) among the two subgroups reached statistical significance in TCGA-COAD datasets (Supplementary Table S3)

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It can suppress natural hormone production by signaling to the brain that the body already has enough testosterone, leading to decreased gonadotropins like LH and FSH