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Consider evening use for recovery: Taking it in the evening can support overnight repair processes and recovery from daily stress or oxidative burden

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While urinary and salivary cortisol levels decreased throughout the day, we also found some slight deviations from this overall pattern: a small cortisol increase was found in both urine (12:00 pm) and saliva (11:45 h)

Plasma will be assessed pre- and post-treatment (baseline and three months) as well as every three months during the 9-month no-treatment follow-up period

The Dutch National Health Counsel and the Regional Disciplinary Medical Board of Eindhoven have stated clearly that vitamin B12 is non-toxic