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Some surgeons open to adjunct therapies though most conservative preferring proven protocols

10.1126/science.1096284 Science 129 VanderkuurJ

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Its structural stability remaining intact under various experimental conditions makes it a reliable reference compound for laboratories investigating tissue repair mechanisms, angiogenic signaling, nitric oxide pathway interactions, and gastrointestinal biology in preclinical settings

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The mechanism difference (tissue repair via angiogenesis vs gene expression modulation) is exactly what makes them complementary in combination formulations rather than substitutes for each other