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TEN significantly reduced glial fibrillary acidic protein immunoreactivity and astrocyte activation, implying that its analgesic effects are associated with suppression of spinal astrocytes and neuroinflammation [36, 37]

Research protocols explore combination approaches with other senolytic compounds such as dasatinib and quercetin, providing frameworks for studying multi-target senolytic strategies and understanding synergistic effects in various experimental models and disease research applications

Its peptide structure breaks down in the digestive system, making a pill version impractical

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