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It has been shown to induce delta sleep in rabbits, rats, mice, dogs, and humans

Yan, M., Xing, G

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used to baseline weight and labs Phase Treatment Duration 24 weeks Notes Once-daily tablet at the assigned dose, alongside calorie-restricted diet Phase Open-label extension (TIPO-4) Duration Up to 48 additional weeks Notes Continued 0.5 mg with optional up-titration to 1.0 mg in some patients Most published efficacy comes from the 24-week treatment window

Many patients maintain weight loss through lifestyle strategies and sometimes continue low-dose maintenance therapy to prevent rebound weight gain