Zllner, View ORCID ProfileSaipavitra Murali-Manohar, Mumuni Abdul-Nashirudeen, Deana Crocetti, Vivek Yedavalli, View ORCID ProfileGeorg Oeltzschner, Natalie Alessi, Mitchell A
The physical and functional intertwining of the ER and mitochondria determines their roles as integrators of cellular signaling, including inflammation, autophagy, and metabolic control ( 2+ overload is closely associated with mPTP opening, dissipation of m, and impairment of oxidative phosphorylation, thereby placing bioenergetic failure among the earliest direct consequences of abnormal ERmitochondria Ca 2+ signaling
E., Heise, A
Treated animals demonstrated a 2.6-fold reduction in tumor incidence, accompanied by a 22.6% decrease in chromosomal abnormalities within bone marrow cells, suggesting potential protective cellular effects
Gene expression and the nervous system Broad Institute Connectivity Map data reveals that GHK influences the expression of a staggering number of human genes, with 50% or greater change in expression in roughly 31% of all human genes examined
2024;doi:10.1001/jamainternmed.2024.4320