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Important contraindications include uncontrolled hypertension, a history of seizure disorders, and current or recent use of opioid medicines

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Shungu DC, Weiduschat N, Murrough JW, Mao X, Pillemer S, Dyke JP, et al

This elegant study dissects the mechanism by which metformin inhibits the mitochondrial respiratory chain complex 1

Though the concept of a healthy microbiota is challenging to define, dysbiosis can usually be defined as a certain imbalance where the pathogenic species are dominant over beneficial symbionts and commensals (Hou et al