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KEY POINTS Antioxidants are substances that neutralise reactive oxygen species (ROS) and free radicals

Synthetic cathinones also impair mitochondrial function, reduce ATP production, and increase the opening of mitochondrial permeability transition pores

Dohnal, V., Wu, Q

These are mechanisms observed primarily in animal and cell-culture models, and they remain an active area of investigation rather than settled clinical fact

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What NAD+ does for the body: Supports the conversion of food into ATP Supports healthy mitochondrial function Helps activate sirtuins, proteins associated with cellular stress response and longevity pathways NAD+ levels naturally decline with age, which has been linked to fatigue, cognitive slowdown, and metabolic inefficiencies