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Nutrients , 15(22), 4809

The risk of gallstones becomes especially concerning during periods of rapid weight loss , a primary goal of GLP-1 therapy

Rybelsus also carries a low risk of hypoglycaemia when used alone or with metformin, as its glucose-dependent mechanism means insulin secretion only occurs when blood glucose is elevated

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Keep them away from spots prone to temperature swings or accidental freezing

Multiple variants in GLP1R have been found to affect how well the receptor responds which is why clinical trials of GLP-1 drugs show some patients lose dramatically more weight than others on the exact same medication