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"When I took it at night, I slept through the side effects but one time I did it in the day and I felt horrendous." He said friends who had taken the peptide had prepared him for these side effects and so he was not concerned about them

K., Schachter, B

Both tirzepatide and retatrutide produce gastrointestinal side effects as their primary adverse reactions, but the frequency, severity, and specific patterns differ between the two compounds