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the bias may result in individuals being selected who better manage their health or receive better care owing to the requirement for persistent utilization and collection of both baseline and follow-up HbA1c and BMI data

some tolerate rapid titration while others require slower schedules or microdose strategies

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While direct head-to-head retinal studies remain limitedmost compare systemic/serum markers or animal modelsemerging evidence from recent research highlights subtle differences: T1DM exhibits a more acute, leukocyte-driven profile with rapid TNF- surges and NLRP3-dominant inflammasome activation in microglia, linked to sudden hyperglycemia (89)

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10.3402/ljm.v9.23055 [DOI] [PMC free article] [PubMed] [Google Scholar] 38.Solverson KJ, Lee H, Doig CJ