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In February 2023, the FDA gave Priority Review to Regenerons investigational antibody, which works by binding to the C5 complement factor, thereby disrupting the complement cascade and preventing associated diseases

Medications, such as those containing phenazopyridine or sulfasalazine, can also cause this coloration

Across ischemic stroke, AD, and PD, enhanced glycolysis, lactate accumulation, and impaired lactate transport consistently emerge as shared metabolic features

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