It was first isolated from human plasma, where it naturally occurs at concentrations of around 200 ng/mL at age 20, declining to approximately 80 ng/mL by age 60
Because only one company manufactures the branded version, supply chain issues have frequently led to nationwide shortages
Implications for weight loss drug marketers: Prescription drug pricing is notoriously confusing, and patients need clear guidance
They are not alone: among others reported to be planning to launch their own generic liraglutide products (the active ingredient in Victoza and Saxenda) are Pfizer, Viatriss Mylan and Novartiss Sandoz
Brinks pointed out that for most people, the cardiometabolic benefits of GLP-1 therapies are substantial and serious vision complications appear uncommon, however, a recent trial demonstrated higher rates of diabetic retinopathy complications, particularly in patients with preexisting disease activity
A drink at dinner or a couple of glasses at an event is not going to unravel a well-run protocol