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The DHT-PGD2-CXXC5 connection A landmark 2023 study published in the journal Cells revealed an even more significant finding

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However, these processes generate considerable amounts of reactive oxygen species (ROS), oxidative stress, and toxic dicarboxylic acids, potentially promoting inflammation and disease progression [78] (Fig

However, the mitochondrial ROS are also responsible for DNA damage, which causes the abundant consumption of NAD + by PARPs

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