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Exercise capacity, measured by the 6-minute walk test, showed that 50% of ARA-290 patients could walk at least 25 meters more compared with only 12% of placebo patients

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Small-molecule pan-ERR agonists extend this paradigm by directly potentiating receptor activity, enabling controlled experimental induction of the exercise program in sedentary animals

Mitochondria are vital for energy production in cells

Excessive iron limitation may impair normal hematopoiesis and neurological development, while inadequate dosing fails to prevent pathogen-induced ferroptosis