doi: 10.2353/ajpath.2010.090682 89 RuggeriRMGiovinazzoSBarbalaceMCCristaniMAlibrandiAVicchioTMet al
Because glutathione is the major intracellular antioxidant defense within a cell, it is proposed that its depletion might be a prerequisite for modulating the apoptotic machinery in autoimmune disease like SLE (Figure 6)
Springer, Singapore (2023)
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Kurbacher CM, Wagner U, Kolster B, Andreotti PE, Krebs D, Bruckner HW
Copper is also bound by regulatory proteins including metallothioneins, copper chaperones (ATOX1, COX17, CCS), and the major plasma copper-binding protein ceruloplasmin