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Taking magnesium immediately before meals may interfere with stomach acid production needed for proper digestion, while taking it too late in the evening might cause sleep disruption in sensitive individuals

Curr Drug Metab 2006

However, it is also crucial to understand that overtraining or exhausted workouts without rest and a healthy diet can deplete glutathione levels in the body

An increased nuclear translocation of Nrf2, an induction of glutathione levels, and subsequent prevention of histological changes in the lens epithelial cells have been observed in rats treated with ferulic acid before and after ionizing radiation exposure

Glutathione may not be beneficial to the body if combined with alcohol consumption