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GLP-1 plays several important roles in metabolic regulation, including stimulating insulin secretion, suppressing glucagon release, and slowing gastric emptying

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Clockaerts S, Van Osch GJ, Bastiaansen-Jenniskens YM, Verhaar JA, Van Glabbeek F, Van Meurs JB, Kerkhof HJ, Hofman A, Stricker BH, Bierma-Zeinstra SM

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Alcohol and smoking deplete glutathione levels and reduce supplement effectiveness