Thus, microbiota-derived purines (especially hypoxanthine) appear to represent vital contributors to, and critical substrates for, colonic barrier function, capacity for mucosal repair, and a healthy microbiota, warranting further exploration and investigation in IBS patients
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Trial design has been published previously
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It was inspired by a fascinating discovery: the Gila monster, a venomous lizard from the American Southwest, produces a compound in its saliva called exendin-4
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