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Anastrozole mimics androgen and reversibly binds to the heme iron of aromatase, thus blocking the action of the enzyme through competitive inhibition
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Additionally, mutation analysis of PRKAR1A was performed using a customized enrichment/hybrid-capture-based panel of genes recurrently altered in brain tumors ( This case represents an interesting molecular profile of an MMNST without PRKAR1A mutation, without any of the reported copy number changes, and without other previously known driver mutations
Understanding the full spectrum of potential side effects enables patients and clinicians to make informed decisions about continuing, adjusting, or discontinuing Mounjaro therapy
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