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Furthermore, it has been shown to be efficacious in other ulcerative colitis models, including models induced by TNBS, cysteamine, surgery, NSAIDs [73,74,75,76,77,78,79,80] or major vessel occlusion [15,16,17,18,19,20,21,22,23]

In this pathway, CoQ10 is crucial, and the inhibition of its synthesis leads to increased LPO (Arslanbaeva et al., 2022)

activity is dependent on a redox-active disulfide in each of the active centres

Rogovski P, Cadamuro RD, da Silva R, de Souza EB, Bonatto C, Viancelli A, et al