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Elevated cortisol, the stress hormone, keeps your nervous system in a state of vigilance incompatible with deep rest

In plain terms: they help your body feel full sooner, stay full longer, and handle food more efficiently

Most doctors begin with a low dose to allow the body to adjust to the medication, then gradually increase it to the target dose

Research indicates that following heroin detoxification treatment, the relapse rate can reach up to 59% within a five-year period [2], potentially linked to the negative emotions experienced during heroin withdrawal

At the highest dose combination tested, people lost 42% of their total body fat mass in 48 weeks of treatment

10.1016/j.addr.2016.06.005 44 MalhotraS.LijnseT.O'CearbhaillE.BraydenD