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In addition to the lean and ob/ob mice, the study included 3-KO mice and WT controls obtained from genetically verified breeding colonies

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B12, or cobalamin, is a complex compound with a cobalt ion at its center

Trying to self-administer comes with real risks, like causing an infection or injuring yourself

Additionally, interactions with concurrent medications (lipid-lowering agents, diabetes medications, stimulants) have not been systematically evaluated

These shots are administered via intramuscular injection (often referred to as IM) so there is no gastrointestinal metabolism, which also allows for increased nutritional absorption