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Excessive secretion of zonulin causes prolongation of the opening time of TJ, which can prolong the abnormal activation of the immune system over time [16, 18, 70,71,72]
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Allergic reactions such as rash, rapid pulse, changes in the taste of food and beverages, acute pancreatitis and thyroid tumors have also been reported as rare effects .
This result justified the extension of the marketing authorization for Mounjaro to the obesity indication at the end of 2023 in Europe
Filippatos TD, Panagiotopoulou TV, Elisaf MS (2014) Adverse effects of GLP-1 receptor agonists