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"S-Adenosylmethionine (SAMe) in major depressive disorder (MDD): a clinician-oriented systematic review"

The decision to restart, switch to a different GLP-1 compound, or try a dual-peptide formulation depends on your goals, tolerability, and response to the first treatment

When the researchers factored in duration of use in secondary analyses, they did detect an increased risk of breast cancer when patients had used GLP-1 analogues for between 2.1 and 3.0 years (hazard ratio [HR] 2.7) and when the time since initiation was between 3.1 and 4.0 years (HR 2.6)

Researchers should also distinguish eumelanin from generic darkening

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