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Yes, in some men, varicocele may contribute to low testosterone levels due to impaired testicular function

Some individuals might use up their B12 reserves quicker than others, requiring more frequent injections

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J Clin Endocrinol Metab 81:33523359 Vaccarello MA, Diamond FB Jr, Guevara-Aguirre J, Rosenbloom AL, Fielder PJ, Gargosky S, Cohen P, Wilson K, Rosenfeld RG (1993) Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/laron syndrome