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126128 These data were confirmed in 2 substudies using the CVD-REAL Nordic database, the first one comparing matched SGLT-2 inhibitor (94% users of dapagliflozin) and other glucose-lowering drug groups, 129 the second one comparing new users of dapagliflozin and new users of DPP-4 inhibitors (Table 6)
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In the harsh conditions of the stomach, the hydrogel would prevent degradation pathways that would break down imatinib from occurring
Additional studies are needed to determine whether SGLT2 inhibitors can meaningfully delay kidney disease progression in people with non-albuminuric or non-proteinuric DKD