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[PubMed: 40206909] [Free PMC Article] Gu YM, Yuan QN, Li X, et al

Whilst vitamin B12 toxicity is exceptionally rare due to its water-soluble nature, very high levelsparticularly from mega-dose supplements or frequent injectionshave been associated with certain adverse effects, most notably skin reactions

Diabetes Care 34:10771080 Solomon L (2016) Vitamin B12-responsive neuropathies: a case series

Vitamin B12 deficiency: Symptoms, causes & treatment

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The study analyzed genetic data from 110 participants to determine if a machine learning-assisted genetic risk score (CTSGRS) could identify patients at higher risk of experiencing side effects