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Moretti M, Bottrighi P, Dallari R, Da Porto R, Dolcetti A, Grandi P, Garuti G, Guffanti E, Roversi P, De Gugliemo M, Potena A (2004) EQUALIFE Study Group

Problematic chronic inflammation: Sustained inflammation (lasting weeks to months) degrades healthy tissue through proteolytic enzymes, reactive oxygen species, inflammatory cytokines (IL-1, TNF-)

Notably, calcium electroporation-a non-thermal ablation method-has shown efficacy in localized PCa treatment

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Parallel reports of matrix metalloproteinase-2 (MMP-2) induction and basement membrane remodeling suggest that TB-500 can transiently loosen ECM constraints, improving contact between follicular structures and the vascular plexus

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