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An invited commentary on this study, also published in JAMA Ophthalmology, challenges the idea that the increased risk of NAION among semaglutide users resulted directly from the medication

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Pharmaceutical companies are also trying to capitalize on the success of this model by rolling out their own platforms: Pfizer rolled out its DTC platform, PfizerForAll, in 2024, and Novo Nordisk launched its direct-to-patient program, NovoCare Pharmacy, in 2025

This raises the possibility that GLP-1 agonists could be used in combination with existing treatments for OUD to improve outcomes for individuals trying to quit opioid use

The 5-session protocol was significantly more effective than the previous 3-session protocol (26.5% vs 10%, p = 0.0025)

And they just become preoccupied with food to the point where its distracting, de Souza said