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By comparison, in the SUSTAIN-7 trial, semaglutide 1 mg weekly (the highest approved dose) achieved approximately 17.5% weight loss

378 Astrocytic overload with iron however significantly reduces glutamate clearance by down-regulation expression of EAAT1 glutamate transporters 379 and impairs operation of the glymphatic system

C'est un tripeptide compos de trois acides amins : l'acide glutamique, la cystine et la glycine