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HAECs had lower levels of iNOS expression, while overexpression of SIRT3 in cells inhibited iNOS expression
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A study revealed that L-methionine supplementation (1.7 g/kg/day, P.O for 8 weeks) was sufficient to produce hyperhomocysteinemia in rats and markedly increased the mean arterial pressure, oxidative stress and mean cardiomyocyte diameter [107]
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