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Patients were initially eligible for surgery if they had a BMI of 40 kg/m 2 or higher, or a BMI between 35 and 40 kg/m 2 with significant comorbidities according to French guidelines [27]

Quality assessment of methods and evidence The methodological quality of the included meta-analyses was assessed using the AMSTAR 2 tool 59

While it sounds outlandish, medical researchers are beginning to investigate whether these drugs act as a general reward dampener

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Figure 20: Photograph of Professor Lelio Orci, credit: University of Geneva, Morriswood

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