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Modulation of DNMT1 activity by ADP-ribose polymers

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[115] reported a fuel-free, zero-waste, non-driven nanomotor for tumor treatment, utilizing biodegradable nanogels that showed long-term and excellent biocompatibility in animal experiments

For now, the agency is monitoring the situation

Safety Profile from Clinical Trials The clinical trials reported that AOD-9604 displayed a very good safety and tolerability profile indistinguishable from placebo for most parameters