Combined, they are studied for broader repair coverage than either alone
Sublingual absorption bypasses the gut entirely no intrinsic factor needed
10.1021/ja01387a013 588 SvedbergT.SjgrenB
Cyanocobalamin is indicated for vitamin B12 deficiencies due to malabsorption which may be associated with the following conditions: Addisonian (pernicious) anemia Gastrointestinal pathology, dysfunction, or surgery, including gluten enteropathy or sprue, small bowel bacteria overgrowth, total or partial gastrectomy Fish tapeworm infestation Malignancy of pancreas or bowel Folic acid deficiency It may be possible to treat the underlying disease by surgical correction of anatomic lesions leading to small bowel bacterial overgrowth, expulsion of fish tapeworm, discontinuation of drugs leading to vitamin malabsorption (see Drug Interactions), use of a gluten-free diet in nontropical sprue, or administration of antibiotics in tropical sprue
In some cases, DSIP enhanced deep sleep, while in others it produced little to no measurable effect
These factors can significantly influence effectiveness