Subramanian, Ichiro Kawachi, Chung-Ying Lin PLOS ONE.2018
Bariatric surgery and cardiovascular outcomes in patients with obesity and cardiovascular disease: a population-based retrospective cohort study
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By activating melanocortin receptors in the central nervous system, it stimulates the pathways that drive arousal and desire a fundamentally different approach from ED medications like sildenafil, which act on blood flow to the genitals
whereas, COX-2 (aka PGH synthase-2) catalyzes it in the inflammatory and cancerous states