Bioactive plant compounds, such as curcumin and resveratrol, inhibit DPP-4 activity in vitro and in diabetic animal models, which can prolong the active form of GLP-1 and contribute to improved glycemic control and modest weight effects in preclinical settings
Second, activated cAMP can also promote the activation of rap guanine nucleotide exchange Factor 4 (RAPGEF4)
79 GastaldelliACusiKFernndez LandLBrayRBrouwersBRodrguez
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