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Khamseekaew J, Kumfu S, Wongjaikam S, Kerdphoo S, Jaiwongkam T, Srichairatanakool S, et al

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This GSH serves as a critical cofactor for GPX4, an enzyme that converts toxic lipid hydroperoxides, such as polyunsaturated fatty acid hydroperoxides (PUFA-OOH), into benign alcohols

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Orforglipron and Pediatric Obesity: Emerging Considerations While clinical development of orforglipron has focused on adults, the pediatric obesity crisis raises inevitable questions about whether oral GLP-1 therapy could eventually reach younger populations