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Male rats were treated with oral doses of 20, 40, and 60 mg/kg/day (6, 13, and 19 times the MRHD on mg/m2 basis) of aripiprazole from 9 weeks prior to mating through mating

The overall risk of mania with/without antidepressants averaged 12.57.5%

Catalase, an antioxidant-rich enzyme, helps protect from oxidative damage and premature aging

In contrast, in cells treated with si-PGC-1 LNP, Poly-A + RNA mainly accumulated in the nucleus, with significantly reduced signals in the cytoplasm, consistent with the results of mRNA nuclear accumulation observed through PCR experiments

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