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Patients want them

The result is a slower, more prolonged alcohol absorptionnot necessarily faster intoxication, but a longer-lasting effect that can surprise people accustomed to their previous drinking patterns

GLP-1 is a naturally occurring hormone released from your small intestine when you eat, says Laster

And billions of people are enjoying a better quality of life, with improvements to their mental and physical health

if indeterminate or high, arrange an Enhanced Liver Fibrosis (ELF) blood test Refer to hepatology if advanced fibrosis is suspected or confirmed on ELF testing Provide lifestyle modification advice focusing on weight loss (710% body weight), Mediterranean-style diet, and increased physical activity (150 minutes of moderate-intensity exercise weekly, in line with NHS guidelines) Advise on alcohol intake in line with UK Chief Medical Officers' guidance (no more than 14 units per week, spread over 3 or more days) Optimise management of diabetes, hypertension, and dyslipidaemia Reassure you that statins are safe and should not be withheld in NAFLD when clinically indicated Patient safety advice : If you develop jaundice (yellowing of skin or eyes), severe abdominal pain, confusion, or vomiting blood, seek urgent medical attention as these may indicate serious liver complications requiring immediate assessment

A gain-of-function mutation of JAK2 in myeloproliferative disorders