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Advantages of 503B Facilities: Direct FDA oversight cGMP requirements (same as drug manufacturers) Regular FDA inspections Mandatory adverse event reporting Can produce larger batches How to Verify: Visit the FDA website and search registered outsourcing facilities to confirm the pharmacy is listed and in good standing

The latest version is published on WADAs website in October and comes into force on 1 January

Further information: MHRA Drug Safety Update (SGLT2 inhibitors and risk of diabetic ketoacidosis), MHRA/EMC Summary of Product Characteristics for GLP-1 receptor agonists, NHS (Pancreatitis, Diabetic ketoacidosis)

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The compound combines GLP-1 receptor agonism with GIP receptor antagonisma novel mechanism informed by human genetics research suggesting GIP inhibition as a key factor in reducing body mass [44]