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Laboratory studies demonstrate that senescent cancer cells maintain similar FOXO4-p53 interactions that protect them from apoptosis, making them susceptible to FOXO4-DRI-mediated elimination while providing researchers with tools for studying cancer cell senescence and survival mechanisms
For example, autoreactive T cells recognizing -synuclein may infiltrate PD brains and kill neurons
[56] More significantly, it influences fat metabolism by promoting the "browning" of energy-storing white adipose tissue into energy-burning brown adipose tissue (BAT)
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