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BPC-157 compound record

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Its selectivity for NNMT (IC50 values in the low micromolar range) means it increases NAD+ by preserving nicotinamide availability rather than directly supplementing NAD+ precursors

Within the Bliss independence model calculation, synergy is assumed when the actual effect of the combination is greater than the expected effect, i.e., if the Bliss score is greater than 0 (40)

Distinct steady-state properties and TNF responses of epithelial long myosin light chain kinase (MLCK) splice variants

2006;44 Suppl 1:1-3