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Tirzepatide Research Highlights Tirzepatide produced larger magnitude effects in body composition research models than Semaglutide at comparable timepoints in head-to-head comparisons
To overcome the very short half-life of GLP-1, DPP-IV inhibitors have been developed
To finish up the side effects, the discontinuation rate excluding the weight loss stoppages appears at least a bit more reasonable as in most obesity trials the stop rate is usually 5-8% which only leaves the 12mg as an outlier still, but like I said earlier, we need side effects over time and just more data in general to see whats going on with that dose
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Research has shown that variations in the OCT1 gene play a significant role in the varying effectiveness of metformin treatment for individuals with T2DM (Gambineri et al., 2010