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Interestingly, tumor cells, by means of somatic copy number alterations (SCNA), can turn off IFN- and IFN- production by homozygously deleting their respective genes (38)

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Drosophila immunofluorescence and image acquisition Wandering third-instar larvae (L3) were obtained by crossing a 2:1 ratio of adult virgin elav-GAL4 females to adult UAS-HA-V5-LaccID males

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However, this does not provide any insight into the role of these variants in islet immune response, cell autoimmunity, cell health and function, and disease onset