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Hepatocytes absorb copper from portal blood, incorporate it into ceruloplasmin and other cuproproteins, and excrete excess copper through bile [2]

Nature Reviews Neuroscience , 3 (6), 473-8

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2.5 Sample preparation After evaluation of seizure behavior, the blood samples were collected from the hearts of all rats under deep anesthesia using 80 mg/kg ketamine with 10 mg/kg xylazine (Ren et al., 2020)

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