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GLP-1 medications typically come in the form of tablets or a once-weekly self-injection with a tiny, virtually painless needle while NAD treatments only come as injections

A GIP receptor agonist exhibits beta-cell anti-apoptotic actions in rat models of diabetes resulting in improved beta-cell function and glycemic control

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CMAJ Canadian Med Assoc J 172(9):11991209

SGLT2i have shown robust effects in reducing heart failure hospitalization and slowing the progression of chronic kidney disease, while GLP-1 RAs have demonstrated superior efficacy in reducing atherothrombotic events, particularly non-fatal stroke

Ultimate results may take one to two years to manifest as swelling dissipates and the tissues settle