Stimulant laxatives (bisacodyl, senna) force colon contractions and should be reserved for occasional use because regular use can train your colon to become dependent
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The medication's appetite-suppressing effects vary considerably between individuals due to differences in metabolism, hormonal regulation, lifestyle factors, and the stage of dose escalation
The result is inconsistent effects, unpredictable appetite suppression , and frustration over why the medication seems to work some weeks and not others
