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GHK-Cu is one of the most extensively characterized signaling peptides in human biology, modulating over 4,000 genes including upregulation of tissue repair, collagen synthesis, and antioxidant defense pathways, while downregulating inflammatory and cellular senescence-associated genes

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It plays a significant role in the maturation and differentiation of T lymphocytes, which are crucial for immune function

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In the dynamic simulation of CME_a, the conformations where these two residues form hydrogen bonds with the ligand represent more than half of all conformations with hydrogen bonds